In the preparation of grignard reagent from inert alkyl bromide, the difficulty of the initiation of the reaction, which reduces the yield, limits its further application. 惰性卤代芳香烃在格氏试剂反应中,由于反应引发困难导致反应收率降低,影响格氏试剂的进一步应用。
Cyclic amide ( incl. cyclic carbamates) and their derivatives ( excl. ureines and their derivatives), and salts thereof Grignard reaction of methyl pyropheophorbide substituted at 3-position by acyl group and synthesis of chlorophyll derivatives 环酰(包括环氨基甲酸酯)及其衍生物(不包括烷基脲及基衍生物)和它们的盐类3-酰基焦脱镁叶绿酸甲酯的格氏反应及其叶绿素衍生物的合成
Grignard reaction of methyl pyropheophorbide substituted at 3-position by acyl group and synthesis of chlorophyll derivatives 3-酰基焦脱镁叶绿酸甲酯的格氏反应及其叶绿素衍生物的合成
Two synthetic methods of organosilicon compounds were adapted. Comparing the merits and demerits of the two methods, we found that it is convenient to use Grignard reagent in the reaction in almost same yield. 采用两种方法对有机硅化合物的合成进行了初步的探索,并比较了两种合成方法的优缺点,发现在产率大致相同的条件下,格式试剂法的后处理比较方便。
The application of this method to other C Grignard reagents and electrophilic reagents give the following results: active electrophilic reagents can carry through the reaction more easily, but require low temperature to reduce the by-products. 将此方法应用于其他碳格氏试剂与亲电试剂,得到如下结论:活泼亲电试剂较容易进行此类反应,但加入亲电试剂的温度需在较低温度下进行,防止副反应。
Synthesis of coenzyme Q using cross-coupling reaction of Grignard reagent Grignard试剂偶联法合成辅酶Q类化合物
Studies on the Reaction of 3-Cyanopyridine with Grignard Reagents 3-氰基吡啶与Grignard试剂的反应研究
The former and 2,7-dibromo-fluorene, 2-bromofluorene were 9-oxidation, and then we attained six 9,9-diaryl-fluorene-based compounds by Grignard reaction and Friedel-Crafts reaction. 后者与2,7-二溴芴、2-溴芴作为起始化合物,分别经过9-位氧化、Grignard反应和Friedel-Crafts烷基化反应三步反应得到六个9,9-二芳基芴化合物。
Mechanism of Grignard Reagent Formation. The Surface Nature of the Reaction 格林亚试剂的形成机理、反应的表面性质
Synthesis of Aromatics by Grignard Reaction with Supersonic Wave as Revulsant 超声波引发格氏反应制备几种香料
Synthesis of 4-( N, N-Dimethylamino) butanal Diethyl Acetal by Grignard Reaction 格氏反应合成4-(N,N-二甲胺基)丁醛缩二乙醇
Research on The Application of Modified BP Neural Networks Model in Grignard Reaction 格氏反应中改进BP神经网络模型的应用研究
Study of CP_2TiCl_2-Catalyzed Reaction of Grignard Reagent with Aryl Aldehydes Cp2TiCl2催化下Grignard试剂与芳醛反应的研究
The results show that the solution of the novel complex can form via the rapid interaction of magnesium, alcohol and alkylogen. The selected alkylogen shall not react with magnesium in the mode of Grignard reaction. 结果表明:将镁、有机醇以及不与镁发生格式反应的卤代烷相互作用可迅速发生反应形成新型含镁络合物溶液。
The very important pharmaceutical intermediate p-fluoro-α-methylstyrene was synthesized using fluorobenzene, bromine and acetone as raw materials via bromination, Grignard reaction and dehydration. 以氟苯、溴和丙酮为原料,通过溴代反应、Grignard反应,再经脱水反应制得医药中间体对氟α-甲基苯乙烯。
The thesis discusses the phenyl chlorine silane cleaner production technologies, and puts forward the synthesis of phenyl trichlorosilane technical route through the application Grignard reaction which can solve shortcomings of traditional methods, that is high energy consumption, more by-products, and environment pollution. 2. 文中论述了苯基氯硅烷的清洁生产工艺,提出了用格氏法合成苯基三氯硅烷的研发思路,从根本上解决传统方法能耗高、副产物多,环境污染的缺点。